Adenomyosis and spontaneous uterine rupture in the second trimester of pregnancy: case report
Adenomiosis y ruptura uterina espontánea en el segundo trimestre de embarazo: reporte de caso
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Introduction:
Adenomyosis is a common gynecological condition; however, cases of uterine rupture leading to fatal complications are rare, particularly in primiparous patients with no history of uterine surgery.
Case report:
We report the case of a 27-year-old patient, Gravida 1, Para 0 patient who was in her second trimester of pregnancy and had a history of adenomyosis (ultrasound diagnosis) and endometriosis (laparoscopy history). She was admitted to the emergency room due to abdominal pain, with no other associated symptoms, with normal fetal monitoring. Shortly after admission, she experienced hemodynamic deterioration and developed signs of peritoneal irritation, which necessitated an urgent laparotomy. During the procedure, we discovered a fetus in the abdominal cavity and hemoperitoneum. Fetus with respiratory effort and pulse in the umbilical cord weighing 789 grams, required cardiopulmonary resuscitation, with subsequent death.
Conclusion:
This type of patient should be counseled about the rare but possible risk of uterine rupture, subsequent maternal and perinatal complications such as spontaneous abortion, preeclampsia, small fetus for gestational age, premature birth and cesarean section. In addition, they should be informed about clear warning signs to go to the nearest health center with obstetrics service. The most frequent signs associated with uterine rupture include: sudden onset of intense abdominal pain associated with hypovolemic shock, uterine hypersensitivity and decelerations of the fetal heart rate.
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- 1. Zhan W, Zhu J, Hua X, Ye J, Chen Q, Zhang J. Epidemiology of uterine rupture among pregnant women in China and development of a risk prediction model: Analysis of data from a multicentre, cross-sectional study. BMJ Open. 2021 Nov 29;11(11). doi: 10.1136/bmjopen-2021-054540.
- 2. Tanos V, Toney ZA. Uterine scar rupture - Prediction, prevention, diagnosis, and management. Best Pract Res Clin Obstet Gynaecol. 2019 Aug 1;59:115–31. doi: 10.1016/j.bpobgyn.2019.01.009. doi: 10.1016/j.pog.2014.11.006.
- 3. Rotura uterina (actualizado julio de 2013). Progresos de Obstetricia y Ginecología [Internet]. 2015 Jun 1 [cited 2025 Jan 20];58(6):296–9. doi: 10.1016/j.pog.2014.11.006.
- 4. Zhao P, Su C, Wang C, Xu J, Bai X. Clinical characteristics of uterine rupture without previous Cesarean section: A 25-year retrospective study. Journal of Obstetrics and Gynaecology Research. 2021 Jun 1;47(6):2093–8. doi: 10.1111/jog.14761.
- 5. Zwart JJ, Richters JM, Öry F, De Vries JIP, Bloemenkamp KWM, Van Roosmalen J. Uterine rupture in the Netherlands: a nationwide population-based cohort study. BJOG. 2009 Jul 1;116(8):1069–80. doi: 10.1111/j.1471-0528.2009.02136.x.
- 6. Vimercati A, Dellino M, Suma C, Damiani GR, Malvasi A, Cazzato G, et al. Spontaneous Uterine Rupture and Adenomyosis, a Rare but Possible Correlation: Case Report and Literature Review. Diagnostics. 2022 Jul 1;12(7). doi: 10.3390/diagnostics12071574.
- 7. Savukyne E, Bykovaite-Stankeviciene R, Machtejeviene E, Nadisauskiene R, Maciuleviciene R. Symptomatic uterine rupture: A fifteen year review. Medicina (Lithuania). 2020 Nov 1;56(11):1–7. doi: 10.3390/medicina56110574.
- 8. Wendel MP, Magann EF. The Impact of Adenomyosis on Pregnancy and Pregnancy Outcomes: A Review. Obstet Gynecol Surv 2022 Aug 1;77(8):495–500. doi: 10.1097/OGX.0000000000001042.
- 9. Van den Bosch T, de Bruijn AM, de Leeuw RA, Dueholm M, Exacoustos C, Valentin L, et al. Sonographic classification and reporting system for diagnosing adenomyosis. Ultrasound Obstet Gynecol. 2019 May 1;53(5):576–82. doi: 10.1002/uog.19096.
- 10. Harmsen MJ, Van den Bosch T, de Leeuw RA, Dueholm M, Exacoustos C, Valentin L, et al. Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure. Ultrasound in Obstetrics & Gynecology. 2022 Jul 1;60(1):118. doi: 10.1002/uog.24786.
- 11. Azziz R. Adenomyosis in pregnancy. A review. Journal of Reproductive Medicine for the Obstetrician and Gynecologist. 1986;31(4):224–7. PMID: 3712359.
- 12. Bensaid F, Kettani F, El Fehri S, Chraibi C, Alaoui MT. Les complications obstetricales de l’adenomyose. Revue de la litterature, a propos de 2 observations. J Gynecol Obstet Biol Reprod (Paris). 1996;25(4):416–8.
- 13. Mueller MD, Saile G, Brühwiler H. SPONTANE UTERUSRUPTUR IN DER 18. SCHWANGERSCHAFTSWOCHE BEI EINER PRIMIGRAVIDA MIT EINER AUSGEDEHNTEN ADENOMYOSE. Zentralbl Gynakol. 1996;118(1):42–4. PMID: 8588451.
- 14. Pafumi C, Farina M, Pernicone G, Russo A, Bandiera S, Giardina P, et al. Adenomyosis and uterus rupture during labor. Chinese Medical Journal (Taipei). 2001;64(4):244–6. PMID: 11458763.
- 15. Li X, Li C, Sun M, Li H, Cao Y, Wei Z. Spontaneous unscarred uterine rupture in a twin pregnancy complicated by adenomyosis A case report. Medicine (United States). 2021;100(3). doi: 10.1097/MD.0000000000024048.
- 16. Nikolaou M, Kourea HP, Antonopoulos K, Geronatsiou K, Adonakis G, Decavalas G. Spontaneous uterine rupture in a primigravid woman in the early third trimester attributed to adenomyosis: A case report and review of the literature. Journal of Obstetrics and Gynaecology Research. 2013 Mar;39(3):727–32. doi: 10.1111/j.1447-0756.2012.02042.x.
- 17. Villa G, Mabrouk M, Guerrini M, Mignemi G, Colleoni GG, Venturoli S, et al. Uterine Rupture in a Primigravida with Adenomyosis Recently Subjected to Laparoscopic Resection of Rectovaginal Endometriosis: Case Report. J Minim Invasive Gynecol. 2008 May;15(3):360–1. doi: 10.1016/j.jmig.2007.10.011.
- 18. Indraccolo U, Iannicco A, Micucci G. A novel case of an adenomyosis-related uterine rupture in pregnancy. Clin Exp Obstet Gynecol. 2015;42(6):810–1. PMID: 26753492.