Melatonina, leptina, resistencia a la insulina e ingesta dietética durante la rotación laboral de trabajadores por turnos

Melatonina, leptina, resistencia a la insulina e ingesta dietética durante la rotación laboral de trabajadores por turnos Melatonin, leptin, insulin resistance and dietary intake during shift workers’ rotation

Published 2021-03-23


https://doi.org/10.30554/archmed.21.2.4135.2021
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Peñaranda, N. ., Aránzalez, L. H. ., & Mockus, I. . (2021). Melatonina, leptina, resistencia a la insulina e ingesta dietética durante la rotación laboral de trabajadores por turnos: Melatonin, leptin, insulin resistance and dietary intake during shift workers’ rotation. Archivos De Medicina , 21(2). https://doi.org/10.30554/archmed.21.2.4135.2021
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Peñaranda, N. ., Aránzalez, L. H. ., & Mockus, I. . (2021). Melatonina, leptina, resistencia a la insulina e ingesta dietética durante la rotación laboral de trabajadores por turnos: Melatonin, leptin, insulin resistance and dietary intake during shift workers’ rotation. Archivos De Medicina , 21(2). https://doi.org/10.30554/archmed.21.2.4135.2021

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Nelly Peñaranda
Universidad Nacional de Colombia
https://orcid.org/0000-0002-4004-9752 ORCID
Luz Helena Aránzalez
Universidad Nacional de Colombia.
https://orcid.org/0000-0003-0338-5826 ORCID
Ismena Mockus
Universidad Nacional de Colombia
https://orcid.org/0000-0003-2312-5327 ORCID
Show authors biography

Nelly Peñaranda,

Magister en fisiología. División de Lípidos y Diabetes, Departamento de Ciencias Fisiológicas, Facultad de Medicina, Universidad Nacional de Colombia. Bogotá- Colombia. 

Luz Helena Aránzalez,

Magister en Bioquímica-Profesora asociada División de Lípidos y Diabetes, Departamento de Ciencias Fisiológicas, Facultad de Medicina, Universidad Nacional de Colombia. Bogotá

Ismena Mockus,

Especialista en endocrinología - Profesora titular. División de Lípidos y Diabetes, Departamento de Ciencias Fisiológicas, Facultad de Medicina, Universidad Nacional de Colombia.

Introduction: Higher risk of obesity and diabetes were registered in shift workers, as well as modifications in melatonin concentrations.

Objective: To determine changes and correlations of salivary melatonin levels, food intake, serum concentrations of leptin, insulin and glucose and insulin resistance index (IRI) after seven night shifts.

Materials and Methods: Ten male security guards took part in this longitudinal study. Anthropometric variables were measured. After both their daily and night shifts, blood and saliva samples were taken and their food intake was estimated.

Results: After seven nights of work, the levels of melatonin, glycemia and leptin at 1pm were greater. Total consumption of calories increased, at the expense of proteins and carbohydrates. The negative correlation between melatonin and insulin resistance was not statistically significant.

Conclusions: The effects of the night shift over melatonin levels were confirmed the day after the work shift ended. Throughout the night shift, workers consumed more calories, and had higher levels of glycemia increasing the risk of developing obesity and diabetes. Leptin level increases were also observed, which may increment the risk of suffering metabolic syndrome.

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