A descriptive study on Colorectal Cancer in Cova da Beira Portugal and the prognostic value of BCL2 in association with tumor location, TNM Staging, and histological type

Estudio descriptivo sobre Cáncer Colorrectal en Cova da Beira Portugal y el valor pronóstico de BCL2 en asociación con la localización del tumor, Estadificación TNM, y tipo histológico

Objective:to carry out a descriptive study on Colorectal Cancer in Cova da Beira Portugal and the prognostic value of BCL2 in association with tumor location, TNMStaging, and histological type.Materials and Methods: A study was conducted in 29 patients who had curative surgery for Rectal Colon Cancer (CRC) excision in the Cova da Beira Hospital Center with the objective of verifying whether the presence of the BCL2 oncoprotein in neoplastic cells is a predictive factor of the prognosis, also verifying if it is predictive of TNM staging, localization and cell differentiation in Rectal Colon Cancer. Results: the findings of this study coincide with that reported in the literature, it was found that the incidence of CRC is higher in men than in women, the risk of the disease increases with age and the most frequent location of neoplastic lesion is in the left portion of the colon, with a total of 26 cases (89.65%). In addition, statistical association of BCL2 expression with prognosis and with histological differentiation was found. Conclusion: despite the limitations of this study, the data found are related to that reported in the literature and establish a statistical association of BCL2 expression with prognosis and histological differentiation.