CARDIOVASCULAR RISK ASSESSMENT USING THE PREVENT SCALE IN OLDER ADULTS FROM NORTHWESTERN COLOMBIA, 2014-2024
EVALUACIÓN DEL RIESGO CARDIOVASCULAR MEDIANTE LA ESCALA PREVENT EN ADULTOS MAYORES DEL NOROCCIDENTE DE COLOMBIA, 2014-2024
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Introduction: Cardiovascular diseases are the leading cause of global mortality, with a significant increase in recent decades. The PREVENT scale, developed by the American Heart Association, aims to enhance cardiovascular risk prediction by incorporating epidemiological changes and emerging risk factors. External validation is essential to ensure its applicability in specific populations such as the Colombian population.
Objective: To evaluate the calibration and discrimination of the PREVENT scale for cardiovascular risk estimation in older adults from northwestern Colombia and compare it with the pooled cohort equations.
Materials and methods: A prospective cohort study was conducted using public health data from Bucaramanga. Demographic variables, cardiovascular risk factors, and anthropometric and biochemical measurements were included in a representative sample of older adults. Competitive risk regression models and ROC curve analysis were applied to compare the predictive performance of PREVENT and the pooled cohort equations.
Results: A total of 10,541 participants were analyzed, with a mean age of 65.67 years, a female predominance (68.8%), and a high prevalence of hypertension (81.4%) and diabetes (28.2%). PREVENT demonstrated superior discrimination (C-statistic: 0.870; 95% CI 0.862-0.878) compared to the pooled cohort equations (0.852; 95% CI 0.846-0.858; p<0.001), with better calibration in men.
Conclusions: The PREVENT scale exhibited high discriminative capacity and acceptable calibration, outperforming the pooled cohort equations. Its implementation could improve cardiovascular risk prediction and patient stratification in the Colombian population.
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