Clinical and microbiological profile of children with febrile neutropenia following antineoplastic treatments in a hospital in Medellin (Colombia), 2009-2010: case series
Perfil clínico y microbiológico de niños con neutropenia febril posterior a tratamientos antineoplásicos tratados en una institución hospitalaria de Medellín (Colombia), 2009-2010: Estudio de serie de casos
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Martínez Sánchez, L. M., Palacio Mesa, M. J., Diosa Restrepo, M., Ramírez Pulgarín, S., Rodríguez Gázquez, M. de los A., & Orozco Forero, J. P. (2015). Clinical and microbiological profile of children with febrile neutropenia following antineoplastic treatments in a hospital in Medellin (Colombia), 2009-2010: case series. Archivos De Medicina , 15(1), 25-32. https://doi.org/10.30554/archmed.15.1.336.2015
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Martínez Sánchez, L. M., Palacio Mesa, M. J., Diosa Restrepo, M., Ramírez Pulgarín, S., Rodríguez Gázquez, M. de los A., & Orozco Forero, J. P. (2015). Clinical and microbiological profile of children with febrile neutropenia following antineoplastic treatments in a hospital in Medellin (Colombia), 2009-2010: case series. Archivos De Medicina , 15(1), 25-32. https://doi.org/10.30554/archmed.15.1.336.2015
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and paraclinical variables. Research included approval of the Ethics Committee. The program SPSS ® version 19.0 was used for processing the information obtained, and its analysis. Results: the average age of the first episode was 5.2±2 years. 50% of the cases were female. The most frequent clinical findings were tachycardia, vomiting, and diarrhea. Statistically significant differences were observed in the count of total
leukocytes and neutrophils; the first with a tendency to decline between episodes, while neutrophils were increased from the first to the second episode, and reduction during the third one. The main sources of infection were the oral mucosa (15,9%), gastrointestinal tract (15,9%) and lung (11,1%). Staphylococcus were the etiological agents most frequently reported with a 12,8% of the total number of episodes. Conclusion: febrile neutropenia secondary to anti-cancer treatments, predisposes to various infectious diseases of variable etiology, developing a wide symptomatology and impacting on the health of patients.
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