Evaluation of the effect of loss to followup in a cohort of children under 1 year of age in Huancavelica and Loreto, Peru
Evaluación del efecto de las pérdidas de seguimiento de una cohorte de niños menores de 1 año de edad en Huancavelica y Loreto, Perú
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Objective: The article presents the methodological design of the cohort of children in Peru, as well as an analysis of possible biases in the estimation of the height-for-age z-score (HAZ) due to the losses to follow-up of the cohort.
Materials and Methods: The cohort of children was developed to identify the causes of chronic childhood malnutrition in Huancavelica and Loreto. Children who were born in previously identified health facilities were enrolled. The follow-up was given from the first month to the first year of the child's life. Through home visits, information related to sociodemographic aspects, food security, food consumption, anthropometry and hemoglobin was collected; at each stage of the cohort. Losses to follow-up represented participants who stopped being evaluated due to rejection or were not found at home.
Results: 1508 children were enrolled (748 in Huancavelica and 760 in Loreto), the losses to follow-up represented 39.7% and 26.4% in Huancavelica and Loreto respectively. During enrollment there was a higher prevalence of ICD in Huancavelica (11.8%) than in Loreto (7.7%) (p value = 0.001). Likewise, losses to follow-up did not affect HAZ (p value = 0.461 CI: -0.18; 0.08)
Conclusions: The cohort study had losses to follow-up within the estimates. Loss to follow-up did not affect the indicator related to chronic childhood malnutrition (HAZ). The study provides adequate evidence to establish the factors associated with chronic childhood malnutrition.
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